Cervical Cancer

ANRS

davy.vandenbroeck — Wed, 27 Jun 2007 12:55:29 +0200

PARTNERS

ICRH, University of Ghent, Belgium
Laboratoire debactériologie-virologie, Université de Montepellier, France
IRS, Moltepellier, France
ICRH, Mombasa, Kenya
Centre MURAZ, Bobo-Dioulasso, Burkina-Faso

OBJECTIVES

Main objective:

to strenghten the capacity of two clinical research sites in Africa

Specific objectives:

Integration of the diagnosis and management of cervical neoplasia in the curriculum of nursery, medicine and gynaecology

peter.decat — Tue, 26 Jun 2007 15:44:21 +0200

PARTNERS

Clara Gonzalez, Magdalena Gonzalez, Alvaro Garcia, Universidad Nacional Autonoma de Nicaragua

OBJECTIVES

General Objectives

To reduce the incidence, morbidity and mortality related to cervical cancer in Nicaragua.
To upgrade the curricula of nursery, medicine and gynaecology at UNAN-Managua to international standards

Specific Objectives

Management of cervical dysplasia in HIV positive women

patricia.claeys — Mon, 11 Jun 2007 11:42:21 +0200

PARTNERS

Dr Othigo, Coast Provincial General Hospital Mombasa
J Bogers, E Van Marck, University Antwerp
Chris Verhofstede, AIDS Reference Laboratory, Ghent University

OBJECTIVES

To assess the effectiveness of outpatient management of precancerous lesions of the cervix in HIV positive women and to identify predictors for progression

METHODS

Natural history and role of HPV in recurrence of dysplasia after treatment of precancerous lesions of the cervix

patricia.claeys — Mon, 11 Jun 2007 11:42:21 +0200

PARTNERS

Elisabeth Beerens, Claude Cuvelier, Marleen Praet, Department of Anatomopathology, Ghent University
Alvaro Gonzalez, Universidad Nacional Autonoma de Nicaragua (UNAN-Managua)

OBJECTIVES

To describe the natural history of HPV infection in women who have been treated for CIN
To assess the relevance of persistent HPV infection in women as a prognostic marker for recurrence after treatment for CIN.

METHODS

Mombasa Cervical Cancer Screening Project

patricia.claeys — Mon, 11 Jun 2007 11:42:20 +0200

PARTNERS

Marc Dhont, Department of Obstetrics and Gynaecology, Ghent University
David Kirumira, Institute of Public Health, Makerere University, Kampala, Uganda
Lucy Muchiri, Department of Human Pathology, University of Nairobi, Kenya
Flavia Lillo, Fondazione Centro Rafaelle del Monte Tabor, Laboratory of Virology, Milan, Italy
Dr Kahinda, Coast Provincial General Hospital, Mombasa, Kenya

OBJECTIVES

Cervical cancer screening in Primay Health Care

patricia.claeys — Mon, 11 Jun 2007 11:42:20 +0200

PARTNERS

Clara Gonzalez, Alvaro Garcia, Universidad Nacional Autonoma de Nicaragua
Rosa Elena Bello, Servicios Medicos Comunales, San Juan del Sur

OBJECTIVES

To improve the reproductive health of Nicaraguan women through the implementation of an adequate, integrated pilot programme for cervical cancer screening at 3 levels (population, health care centre, district hospital).

METHODS

Management of sexually transmitted infections and precancerous lesions

patricia.claeys — Mon, 11 Jun 2007 11:42:20 +0200

PARTNERS

Magdalena Gonzalez, Clara Gonzalez, Universidad Nacional Autonoma de Nicaragua

OBJECTIVES

To assess strategies for an efficient detection and treatment of cervical cancer and STDs among Nicaraguan women.

METHODS

Consecutive women attending women's health clinics in different regions (Managua, Rivas and Matagalpa) were interviewed and examined for STI, HIV, and cervical neoplasia

RESULTS

Cervical cancer and sexually transmitted diseases

patricia.claeys — Mon, 11 Jun 2007 11:42:22 +0200

PARTNERS

Job Bwayo, Department of Medical Microbiology, University of Nairobi, Kenya
Family Planning Association of Kenya

OBJECTIVES

General objective:

To assess the feasibility of interventions for primary and secondary prevention interventions to improve women's reproductive health (cervical cancer screening).

Specific objective:

To validate and enhance the specificity of visual inspection (VIA) versus PAP smear.

METHODS

University of Nairobi collaboration

davy.vandenbroeck — Mon, 11 Jun 2007 11:42:21 +0200

PARTNERS

ICRH, University of Ghent, Belgium
Kenyatta Universital Hospital, University of Nairobi, Kenya

OBJECTIVES

To determine prevalences, viral parameters of HIV and HPV and its relation to cervical neoplasia in the general population of Nairobi
To determine the effect of contraceptives on the HIV viral transmission/shedding
To determine the effect of cytokines and immune components on HIV transmission/shedding

METHODS